解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:OBJECTIVE:To establish a baseline of national practice for follow-up after treatment for gynaecological cancer. DESIGN:Questionnaire survey. SETTING:Gynaecological cancer centres and units. GEOGRAPHICAL LOCATION UK PARTICIPANTS:Members of the British Gynaecological Cancer Society and the National Forum of Gynaecolog...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002859
更新日期:2013-07-24 00:00:00
abstract:INTRODUCTION:Coping skills training interventions have been found to be efficacious in helping both patients and their partners manage the physical and emotional challenges they face following a cancer diagnosis. However, many of these interventions are costly and not sustainable. To overcome these issues, a self-direc...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003337
更新日期:2013-07-24 00:00:00
abstract:INTRODUCTION:Tubal ectopic pregnancy (tEP) is the most common life-threatening condition in gynaecology. tEPs with pretreatment serum human chorionic gonadotrophin (hCG) levels <1000 IU/L respond well to outpatient medical treatment with intramuscular methotrexate (MTX). TEPs with hCG >1000 IU/L take a significant time...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002902
更新日期:2013-07-19 00:00:00
abstract:OBJECTIVES:The aim of this systematic review was to examine the epidemiology of malpractice claims in primary care. DESIGN:A computerised systematic literature search was conducted. Studies were included if they reported original data (≥10 cases) pertinent to malpractice claims, were based in primary care and were pub...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002929
更新日期:2013-07-18 00:00:00
abstract:BACKGROUND:Clinical trials on Traditional Chinese Medicine (TCM) should be registered in a publicly accessible international trial register and report on all outcomes. We systematically assessed and evaluated TCM trials in registries with their subsequent publications. OBJECTIVE:To describe the characteristics of TCM ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002968
更新日期:2013-07-16 00:00:00
abstract:OBJECTIVES:Mortality has declined in people with HIV infection, subsequent to the improved access to antiretroviral therapy (ART). We assessed the incidence and determinants of mortality among patients with HIV-1 infection who were started on ART in a referral treatment centre for HIV infection in Yaounde, Cameroon. D...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003210
更新日期:2013-07-13 00:00:00
abstract:INTRODUCTION:High-grade gliomas (HGGs) are the most malignant type of brain tumours. The 5-year survival is 10% and a significant part of the ongoing research aims to increase survival through surgical and oncological treatments. Accordingly, there is an increasing need for investigating the HGG trajectory in order to ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003183
更新日期:2013-07-11 00:00:00
abstract:OBJECTIVES:The rate of total knee arthroplasty surgery (TKA) is rising in Australia despite varying impacts of TKA on physical function (PF) in population-based studies. There are potentially modifiable risk factors that could enhance PF after TKA, so we evaluated (1) the levels of PF in persons with TKA and the rest o...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002291
更新日期:2013-07-08 00:00:00
abstract:OBJECTIVE:To determine if low-dose weekly chloroquine (CQ) therapy improves recovery from malaria-associated anaemia. DESIGN:Proof of concept randomised clinical trial. SETTING:West Kiang District, Lower River Region, The Gambia. PARTICIPANTS:Children resident in participating communities, aged 12-72 months, with un...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002666
更新日期:2013-07-04 00:00:00
abstract:OBJECTIVE:To evaluate the impact of (1) the removal of home access to traditional electronic games or (2) their replacement with active input electronic games, on daily physical activity and sedentary behaviour in children aged 10-12 years. DESIGN:Crossover randomised controlled trial, over 6 months. SETTING:Family h...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002629
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVES:Medical and healthcare organisations-including the national cancer support and helpline organisation that is the subject of this study-are expected to collect and monitor information about the ethnicity of their client populations. Information about ethnicity is important for a variety of reasons, including ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002676
更新日期:2013-06-28 00:00:00
abstract:INTRODUCTION:Mobile phone ownership and use are growing fastest in sub-Saharan Africa, and there is evidence that mobile phone text messages can be used successfully to significantly improve adherence to antiretroviral therapy and reduce treatment interruptions. However, the effects of many mobile health interventions ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002816
更新日期:2013-06-25 00:00:00
abstract:OBJECTIVES:To identify rates of potentially preventable complications for dementia patients compared with non-dementia patients. DESIGN:Retrospective cohort design using hospital discharge data for dementia patients, case matched on sex, age, comorbidity and surgical status on a 1 : 4 ratio to non-dementia patients. ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002770
更新日期:2013-06-20 00:00:00
abstract:OBJECTIVES:To investigate the role of socioeconomic status and psychological stress to potential associations between confidence in the future and a wide range of health-related behaviours. DESIGN:Web-based cross-sectional study including an 'Electronic Health Check' at the Finnish Happiness-Flourishing Study website ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002397
更新日期:2013-06-20 00:00:00
abstract:OBJECTIVE:To examine the effect of an outdoor smokefree law in parks and on beaches on observed smoking in selected venues. METHODS:The study involved repeated observations in selected parks and beaches in Vancouver, British Columbia, Canada. The main outcome measure was changes in observed smoking rates in selected v...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002916
更新日期:2013-06-20 00:00:00
abstract:INTRODUCTION:Evidence from animal studies suggest that the rate of ageing may be influenced not only by genetic and lifestyle factors, but also by the prenatal environment. We have previously shown that people who were exposed to famine during early gestation performed worse on a selective attention task, which may be ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-003167
更新日期:2013-06-20 00:00:00
abstract:OBJECTIVES:This cross-sectional survey investigated whether there were ethnic differences in depressive symptoms among British South Asian (BSA) patients with cancer compared with British White (BW) patients during 9 months following presentation at a UK Cancer Centre. We examined associations between depressed mood, c...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002650
更新日期:2013-06-20 00:00:00
abstract:OBJECTIVES:To identify the sociodemographic factors associated with variation in area-based breastfeeding in England; to calculate the predicted breastfeeding rates adjusted for sociodemographic variations. DESIGN:Ecological analysis of routine data using random effects logistic regression. SETTING:All 151 primary ca...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002765
更新日期:2013-06-20 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine the current work distribution of health professionals from a public Ugandan medical school in a period of major donor funding for HIV programmes. We explore the hypothesis that programmes initiated under unprecedented health investments from the US President's Emerge...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002875
更新日期:2013-05-31 00:00:00
abstract:OBJECTIVES:To compare the costs and cost-effectiveness of managing patients with uncontrolled blood pressure (BP) using telemonitoring versus usual care from the perspective of the National Health Service (NHS). DESIGN:Within trial post hoc economic evaluation of data from a pragmatic randomised controlled trial using...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002681
更新日期:2013-05-28 00:00:00
abstract:OBJECTIVES:To analyse the parental understanding of informed consent information in first-line randomised clinical trials (RCTs) including children with malignant solid tumours and to assess parents' needs for decision-making. DESIGN:Observational prospective study. SETTING:3 paediatric oncology centres in the Parisi...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002733
更新日期:2013-05-28 00:00:00
abstract:INTRODUCTION:Cannabis use and dependence is a serious health and criminal justice issue among incarcerated populations internationally. Upon abrupt, enforced cessation of cannabis, prisoners may suffer irritability and anger that can lead to threatening behaviour, intimidation, violence, sleep disturbances and self-har...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002951
更新日期:2013-05-28 00:00:00
abstract:OBJECTIVE:To estimate the time spent by the researchers for preparing grant proposals, and to examine whether spending more time increase the chances of success. DESIGN:Observational study. SETTING:The National Health and Medical Research Council (NHMRC) of Australia. PARTICIPANTS:Researchers who submitted one or mo...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002800
更新日期:2013-05-28 00:00:00
abstract:OBJECTIVE:To assess the inclusion of patients as international research partners in Outcome Measures in Rheumatology (OMERACT) conferences and how this has influenced the scope and conduct of outcomes research in rheumatology. DESIGN:A thematic content analysis of OMERACT internal documents, publications and conferenc...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002241
更新日期:2013-05-09 00:00:00
abstract:OBJECTIVES:To evaluate surgical experience among current doctors appointed into ophthalmology training posts since the introduction of the Modernising Medical Careers programme. Additionally, to identify regional variations in surgical experience and training programme delivery. DESIGN:A cross-sectional survey. SETTI...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002578
更新日期:2013-05-06 00:00:00
abstract:OBJECTIVE:To assess scientific publication and map research gaps on access to medicines (ATM) in Latin American and the Caribbean low-income and middle-income countries (LMIC). DESIGN:Scoping review. Two independent reviewers assessed studies for inclusion and extracted data from each study. INFORMATION SOURCES:Searc...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002224
更新日期:2013-05-03 00:00:00
abstract:OBJECTIVE:The aim of this study was to develop a framework and best estimates of prevalence for the most at risk populations (MARPs) for HIV/AIDS to include sex workers (SW), men who have sex with men (MSM) and injecting drug users (IDUs) in order to evaluate national HIV/AIDS programmatic targets across the Republic o...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002203
更新日期:2013-05-02 00:00:00
abstract:OBJECTIVES:To examine whether providing thermal clothing to heart failure patients improves their health during winter. DESIGN:A randomised controlled trial with an intervention group and a usual care group. SETTING:Heart failure clinic in a large tertiary referral hospital in Brisbane, Australia. PARTICIPANTS:Eligi...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002799
更新日期:2013-04-29 00:00:00
abstract:OBJECTIVES:To describe the long-term clinical outcomes after cataract surgery with and without capsular tension ring (CTR) in a group of patients with retinitis pigmentosa (RP). DESIGN:A retrospective study. SETTING:Tertiary referral centre. PARTICIPANTS:52 eyes (46 patients) with RP. INTERVENTIONS:Cataract surgery...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002616
更新日期:2013-04-26 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess the risk of injuries among children exposed to a stressful life exposure (defined as bereavement) before conception or during fetal life. DESIGN:Population-based cohort study. SETTING:Denmark. PARTICIPANTS:All singleton births in Denmark between 1 January 1995 and 31 De...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002357
更新日期:2013-04-22 00:00:00
abstract:OBJECTIVES:To prevent pain inhibiting their performance, many athletes ingest over-the-counter (OTC) analgesics before competing. We aimed at defining the use of analgesics and the relation between OTC analgesic use/dose and adverse events (AEs) during and after the race, a relation that has not been investigated to da...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002090
更新日期:2013-04-19 00:00:00
abstract:OBJECTIVES:To examine the extent of primary care follow-up and mental health outcomes among women referred for ultrasound assessment of pain and/or bleeding in early pregnancy, including those whose pregnancy is found to be viable on ultrasound assessment. DESIGN:Questionnaire study with prospective follow-up. SETTIN...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002595
更新日期:2013-04-11 00:00:00
abstract:OBJECTIVE:Despite the increasing numbers of published trials of quality improvement (QI) interventions in diabetes, little is known about the risk of bias in this literature. DESIGN:Secondary analysis of a systematic review. DATA SOURCES:Medline, the Cochrane Effective Practice and Organisation of Care (EPOC) databas...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-002727
更新日期:2013-04-09 00:00:00
abstract:BACKGROUND:The juvenile form of Huntington's disease (HD) is a rare disorder. There are no population-based estimates of either its incidence or prevalence in any population in the world. The present study was undertaken to estimate the frequency of juvenile HD in the UK and to examine the range of pharmacological trea...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002085
更新日期:2013-04-03 00:00:00
abstract:OBJECTIVE:To test agreement of two methods to measure intraocular pressure (IOP): rebound tonometry (RBT) and gold standard Goldmann applanation tonometry (GAT) in children with glaucoma. DESIGN:Observational prospective cohort study. SETTING:Tertiary paediatric glaucoma clinic at a single centre. PARTICIPANTS:102 i...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-001788
更新日期:2013-04-02 00:00:00
abstract:OBJECTIVE:To compare the efficacy of Food and Drug Administration recommended dosing of nicardipine versus labetalol for the management of hypertensive patients with signs and/or symptoms (S/S) suggestive of end-organ damage (EOD). DESIGN:Secondary analysis of the multicentre prospective, randomised CLUE trial. SETTI...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002338
更新日期:2013-03-26 00:00:00
abstract:OBJECTIVES:To examine the patterns of social inequalities in anaemia over time among women of reproductive age in India. DESIGN:Repeated cross-sectional study using nationally representative data from the 1998/1999 and 2005/2006 National Family Health Surveys of India. Multivariate modified Poisson regression models w...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002233
更新日期:2013-03-19 00:00:00
abstract:OBJECTIVE:To determine whether elevated blood cobalt (Co) concentrations are associated with early failure of metal-on-metal (MoM) hip resurfacings secondary to adverse reaction to metal debris (ARMD). DESIGN:Cohort study. SETTING:Single centre orthopaedic unit. PARTICIPANTS:Following the identification of complicat...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-001541
更新日期:2013-03-12 00:00:00
abstract:OBJECTIVE:Primarily to develop a multimarker score for prediction of 3-year mortality in older patients with decompensated heart failure (HF). DESIGN:Prospective cohort study. SETTING:Secondary care. Single centre. PATIENTS AND BIOMARKERS: 131 patients, aged ≥65 years, with decompensated HF were included. Assessment ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002254
更新日期:2013-03-09 00:00:00
abstract:OBJECTIVES:Cadmium exposure has been found to be associated with atherosclerotic plaques in the carotid arteries and with circulating levels of the proatherogenic intercellular adhesion molecule-1 (ICAM-1). The research questions were (1) if blood and urinary cadmium levels are associated with low ankle-brachial index ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-002489
更新日期:2013-03-06 00:00:00